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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $113 | In Stock | |
2 mg | $158 | In Stock | |
5 mg | $233 | In Stock | |
10 mg | $351 | In Stock | |
25 mg | $593 | In Stock | |
50 mg | $846 | In Stock | |
100 mg | $1,170 | In Stock | |
1 mL x 10 mM (in DMSO) | $285 | In Stock |
Description | Indophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM. Indophagolin antagonizes the purinergic receptor P2X4 as well as P2X1 and P2X3 with IC50s of 2.71, 2.40 and 3.49 μM, respectively. |
In vitro | Indophagolin (10 μM) inhibits autophagosome formation in MCF7 cells.Indophagolin also antagonizes the Gq-protein-coupled P2Y4, P2Y6, and P2Y11 receptors (IC50s =3.4~15.4 μM). Indophagolin has a strong antagonistic effect on serotonin receptor 5-HT6 (IC50=1.0 μM) and a moderate effect on receptors 5-HT1B, 5-HT2B, 5-HT4e, and 5-HT7. |
Molecular Weight | 523.75 |
Formula | C19H15BrClF3N2O3S |
Cas No. | 1207660-00-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||
Solubility Information | DMSO: 25 mg/mL (47.73 mM) ![]() | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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