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Pamidronate Disodium

🥰Excellent
Catalog No. T1337Cas No. 57248-88-1
Alias Pamidronate disodium salt, CGP 23339AE, CGP 23339A

Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones.

Pamidronate Disodium

Pamidronate Disodium

🥰Excellent
Purity: 99.94%
Catalog No. T1337Alias Pamidronate disodium salt, CGP 23339AE, CGP 23339ACas No. 57248-88-1
Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones.
Pack SizePriceAvailabilityQuantity
5 mg$38In Stock
10 mg$52In Stock
25 mg$82In Stock
50 mg$138In Stock
100 mg$198In Stock
200 mg$297In Stock
500 mg$512In Stock
1 mL x 10 mM (in H2O)$42In Stock
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Purity:99.94%
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Product Introduction

Bioactivity
Description
Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones.
In vitro
In ovariectomized rats, Pamidronate significantly enhanced bone density and trabecular weight. Additionally, in rats treated with Growth Hormone (GH), Pamidronate reduced the levels of IGF-I.
In vivo
In human osteoblast-like cells, Pamidronate (1 μM) enhances the level of OPG mRNA and protein secretion in a dose-dependent manner. Additionally, in mouse osteoclast-like cells (IC50=0.58 μM), Pamidronate inhibits the resorption of calcium phosphate films.
AliasPamidronate disodium salt, CGP 23339AE, CGP 23339A
Chemical Properties
Molecular Weight279.03
FormulaC3H9NNa2O7P2
Cas No.57248-88-1
Smiles[Na+].[Na+].NCCC(O)(P(O)([O-])=O)P(O)([O-])=O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: Insoluble
H2O: 10 mM
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM3.5838 mL17.9192 mL35.8384 mL179.1922 mL
5 mM0.7168 mL3.5838 mL7.1677 mL35.8384 mL
10 mM0.3584 mL1.7919 mL3.5838 mL17.9192 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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