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Progabide
🥰Excellent
Catalog No. T16581Cas No. 62666-20-0
Alias SL 76002, Halogabide, Gabrene, Gabren
Progabide (SL 76002) is an agonist of the gamma-aminobutyric acid receptor.
Progabide
🥰Excellent
Purity: 99.7%
Catalog No. T16581Alias SL 76002, Halogabide, Gabrene, GabrenCas No. 62666-20-0
Progabide (SL 76002) is an agonist of the gamma-aminobutyric acid receptor.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $30 | In Stock | |
| 10 mg | $48 | In Stock | |
| 25 mg | $98 | In Stock | |
| 50 mg | $158 | In Stock | |
| 100 mg | $248 | In Stock | |
| 200 mg | $353 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $31 | In Stock |
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CitedSelect Batch
Purity:99.7%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Progabide (SL 76002) is an agonist of the gamma-aminobutyric acid receptor. |
| In vivo | Progabide ( 50, 100 and 200 mg/kg) given IP to male Wistar rats enhance the plasma corticosterone levels by 244, 365, and 476% respectively (t=6.44 to12.55, p<0.01). Progabide (10 mg/kg) fails to change the concentration of corticosterone in plasma (t=0.76, N.S.). The increased plasma corticosterone level induced by administration of 200 mg/kg Progabide is evident 30 (t=2.625, p<0.05), 60 (t=13.13, p<0.001) and 120 min (t=4.07, p<0.01) after drug injection, but returns to the control value 240 min after drug injection (t=0.86, N.S.). Compare with the corresponding control, The greatest corticosterone rise is reached 60 min following the administration of Progabide[1]. |
| Alias | SL 76002, Halogabide, Gabrene, Gabren |
| Molecular Weight | 334.77 |
| Formula | C17H16ClFN2O2 |
| Cas No. | 62666-20-0 |
| Smiles | NC(=O)CCC\N=C(\c1ccc(Cl)cc1)c1cc(F)ccc1O |
| Relative Density. | 1.2822 g/cm3 (Estimated) |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 225 mg/mL (672.1 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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