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Quinidine

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Catalog No. T7938Cas No. 56-54-2

Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.

Quinidine

Quinidine

🥰Excellent
Purity: 99.99%
Catalog No. T7938Cas No. 56-54-2
Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.
Pack SizePriceAvailabilityQuantity
100 mg$48In Stock
1 mL x 10 mM (in DMSO)$54In Stock
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Purity:99.99%
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Product Introduction

Bioactivity
Description
Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.
In vitro
Quinidine blocks the voltage-gated sodium (Nav) channel Nav1.5 in a use-dependent manner.It decreases the amplitude and duration of action potentials in isolated canine ventricular myocytes[1].
Chemical Properties
Molecular Weight324.42
FormulaC20H24N2O2
Cas No.56-54-2
Smiles[H][C@@]12CCN(C[C@@H]1C=C)[C@H](C2)[C@@H](O)c1ccnc2ccc(OC)cc12
Relative Density.1.1294 g/cm3 (Estimated)
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (154.12 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0824 mL15.4121 mL30.8242 mL154.1212 mL
5 mM0.6165 mL3.0824 mL6.1648 mL30.8242 mL
10 mM0.3082 mL1.5412 mL3.0824 mL15.4121 mL
20 mM0.1541 mL0.7706 mL1.5412 mL7.7061 mL
50 mM0.0616 mL0.3082 mL0.6165 mL3.0824 mL
100 mM0.0308 mL0.1541 mL0.3082 mL1.5412 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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