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Sulbactam

🥰Excellent
Catalog No. T1631Cas No. 68373-14-8
Alias CP45899

Sulbactam (CP45899) is a semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics by the enzyme. Combining this agent with a beta-lactamase susceptible antibiotic, such as penicillins or a cephalosporin, to treat infections caused by beta-lactamase producing organisms, results in a decreased turnover rate of the beta-lactamase sensitive antibiotic and enhances its antibacterial activity.

Sulbactam

Sulbactam

🥰Excellent
Purity: 99.32%
Catalog No. T1631Alias CP45899Cas No. 68373-14-8
Sulbactam (CP45899) is a semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics by the enzyme. Combining this agent with a beta-lactamase susceptible antibiotic, such as penicillins or a cephalosporin, to treat infections caused by beta-lactamase producing organisms, results in a decreased turnover rate of the beta-lactamase sensitive antibiotic and enhances its antibacterial activity.
Pack SizePriceAvailabilityQuantity
50 mg36 €In Stock
100 mg47 €In Stock
200 mg55 €In Stock
500 mg87 €In Stock
1 mL x 10 mM (in DMSO)44 €In Stock
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Purity:99.32%
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Product Introduction

Bioactivity
Description
Sulbactam (CP45899) is a semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics by the enzyme. Combining this agent with a beta-lactamase susceptible antibiotic, such as penicillins or a cephalosporin, to treat infections caused by beta-lactamase producing organisms, results in a decreased turnover rate of the beta-lactamase sensitive antibiotic and enhances its antibacterial activity.
AliasCP45899
Chemical Properties
Molecular Weight233.24
FormulaC8H11NO5S
Cas No.68373-14-8
Smiles[Na+].[H][C@@]12CC(=O)N1C(C([O-])=O)C(C)(C)S2(=O)=O
Relative Density.1.62 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 43 mg/mL (184.4 mM)
DMSO: 70 mg/mL (300.12 mM), Sonication is recommended.
Ethanol: 44 mg/mL (188.6 mM)
Solution Preparation Table
H2O/Ethanol/DMSO
1mg5mg10mg50mg
1 mM4.2874 mL21.4371 mL42.8743 mL214.3715 mL
5 mM0.8575 mL4.2874 mL8.5749 mL42.8743 mL
10 mM0.4287 mL2.1437 mL4.2874 mL21.4371 mL
20 mM0.2144 mL1.0719 mL2.1437 mL10.7186 mL
50 mM0.0857 mL0.4287 mL0.8575 mL4.2874 mL
100 mM0.0429 mL0.2144 mL0.4287 mL2.1437 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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