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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $31 | In Stock | |
5 mg | $72 | In Stock | |
10 mg | $117 | In Stock | |
25 mg | $247 | In Stock | |
50 mg | $389 | In Stock | |
100 mg | $582 | In Stock | |
1 mL x 10 mM (in DMSO) | $312 | In Stock |
Description | Tenapanor (RDX 5791) is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3, which plays a prominent role in sodium handling in the gastrointestinal tract and kidney. Tenapanor possesses an excellent preclinical safety profile and, as of now, there are no serious concerns about its side effects. |
Targets&IC50 | NHE3 (human):5 nM (IC50), NHE3 (rat):10 nM (IC50) |
Alias | RDX-5791, RDX 5791, AZD 1722, Tenapanor free base, RDX5791, AZD-1722, AZD1722 |
Molecular Weight | 1145.05 |
Formula | C50H66Cl4N8O10S2 |
Cas No. | 1234423-95-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (43.67 mM), Sonication is recommended. ![]() H2O: < 0.1 mg/mL (insoluble) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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