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Triclabendazole

Triclabendazole
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Purity:98.35%
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Triclabendazole

Catalog No. T0838Cas No. 68786-66-3
Triclabendazole (CGA89317) has been used in trials studying Parasitic Disease.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
25 mg$44In Stock
50 mg$63In Stock
100 mg$79In Stock
200 mg$102In Stock
500 mg$167In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Product Introduction

Bioactivity
Description
Triclabendazole (CGA89317) has been used in trials studying Parasitic Disease.
In vitro
Triclabendazole treatment produces percentage decreases of the fluke egg output by 15.3%, 4.3% and 36.6%, respectively, in sheep, dairy cows and heifers, these results indicate the presence of TCBZ-resistant Fasciola hepatica in sheep and cattle on this farm. [1] Triclabendazole sulphoxide (50 mg/mL) results in extensive damage to the tegument of triclabendazole-susceptible F. hepatica, whereas triclabendazole-resistant flukes shows only localized and relatively minor disruption of the tegument covering the spines. [2]
AliasCGA89317
Chemical Properties
Molecular Weight359.66
FormulaC14H9Cl3N2OS
Cas No.68786-66-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 60 mg/mL (166.82 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7804 mL13.9020 mL27.8040 mL139.0202 mL
5 mM0.5561 mL2.7804 mL5.5608 mL27.8040 mL
10 mM0.2780 mL1.3902 mL2.7804 mL13.9020 mL
20 mM0.1390 mL0.6951 mL1.3902 mL6.9510 mL
50 mM0.0556 mL0.2780 mL0.5561 mL2.7804 mL
100 mM0.0278 mL0.1390 mL0.2780 mL1.3902 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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