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Zandelisib
🥰Excellent
Catalog No. T13386Cas No. 1401436-95-0
Zandelisib is an inhibitor of phosphatidylinositol 3-kinase (PI3K)(p110δ, IC50 of 3.5 nM), and with antineoplastic activity.
Zandelisib
🥰Excellent
Purity: 99.15%
Catalog No. T13386Cas No. 1401436-95-0
Zandelisib is an inhibitor of phosphatidylinositol 3-kinase (PI3K)(p110δ, IC50 of 3.5 nM), and with antineoplastic activity.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $89 | In Stock | |
| 5 mg | $190 | In Stock | |
| 10 mg | $317 | In Stock | |
| 25 mg | $513 | In Stock | |
| 50 mg | $693 | In Stock | |
| 100 mg | $953 | In Stock | |
| 200 mg | $1,280 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $237 | In Stock |
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CitedSelect Batch
Purity:99.15%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Zandelisib is an inhibitor of phosphatidylinositol 3-kinase (PI3K)(p110δ, IC50 of 3.5 nM), and with antineoplastic activity. |
| Targets&IC50 | PI3Kδ:3.5 nM |
| In vitro | Zandelisib inhibits PI3Ks(p110α, p110β, p110γ and p110δ with IC50s of 4, 976 nM, 605 nM, 817 nM and 3.5 nM, respectivey)[1]. |
| Molecular Weight | 576.68 |
| Formula | C31H38F2N8O |
| Cas No. | 1401436-95-0 |
| Smiles | CN1CCC(CC1)c1ccccc1CC(C)(C)Nc1nc(nc(n1)-n1c(nc2ccccc12)C(F)F)N1CCOCC1 |
| Relative Density. | 1.33 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 33.33 mg/mL (57.80 mM), when pH Adjusted to 3 with HCl. Sonication and heating to 60℃ are recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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