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ML348

ML348
ML348 (GNF-Pf-1127) is a selective, reversible inhibitor of lysophospholipase 1 (LYPLA1) with an IC50 of 210 nM.
Catalog No. T3439Cas No. 899713-86-1
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Purity:99.88%
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ML348

Purity: 99.88%
Catalog No. T3439Alias GNF-Pf-1127Cas No. 899713-86-1

ML348 (GNF-Pf-1127) is a selective, reversible inhibitor of lysophospholipase 1 (LYPLA1) with an IC50 of 210 nM.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
2 mg$39In Stock
5 mg$63In Stock
10 mg$98In Stock
25 mg$239In Stock
50 mg$372In Stock
100 mg$597In Stock
200 mg$833In Stock
500 mg$1,260In Stock
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Product Introduction

Bioactivity
Description
ML348 (GNF-Pf-1127) is a selective, reversible inhibitor of lysophospholipase 1 (LYPLA1) with an IC50 of 210 nM.
Targets&IC50
LYPLA1:210 nM
AliasGNF-Pf-1127
Chemical Properties
Molecular Weight415.79
FormulaC18H17ClF3N3O3
Cas No.899713-86-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 83.33 mg/mL (200.41 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4051 mL12.0253 mL24.0506 mL120.2530 mL
5 mM0.4810 mL2.4051 mL4.8101 mL24.0506 mL
10 mM0.2405 mL1.2025 mL2.4051 mL12.0253 mL
20 mM0.1203 mL0.6013 mL1.2025 mL6.0127 mL
50 mM0.0481 mL0.2405 mL0.4810 mL2.4051 mL
100 mM0.0241 mL0.1203 mL0.2405 mL1.2025 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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Dose Conversion

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