Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 39.00 | |
10 mg | In stock | $ 72.00 | |
25 mg | In stock | $ 147.00 | |
50 mg | In stock | $ 247.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 43.00 |
Description | Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer. |
In vivo | Arimoclomol, administered for 5 d, has a protective effect against CCK-induced acute pancreatitis. Repeated CCK treatment results in the typical laboratory and morphological changes of experimentally induced pancreatitis. The pancreatic levels of HSP60 and HSP72 are significantly increased in the animals treated with Arimoclomol [1]. Arimoclomol is a co-inducer of heat shock proteins for the potential treatment of amyotrophic lateral sclerosis (ALS), the most common form of motor neuron disease [2]. |
Synonyms | BRX-220 |
Molecular Weight | 429.85 |
Formula | C18H24ClN3O7 |
CAS No. | 289893-26-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (581.60 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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Arimoclomol maleate 289893-26-1 Cytoskeletal Signaling Metabolism HSP system neurons Inhibitor motor clearance Arimoclomol BRX 220 Heat shock proteins aggregation ubiquitin BRX-220 misfolded inhibit protein BRX220 proteasome Arimoclomol Maleate assemblies co-inducer inhibitor