Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Cintirorgon (LYC-55716) is a selective, oral agonist of RORγ. Cintirorgon modulates gene expression of RORγ expressing T lymphocyte immune cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 77.00 | |
5 mg | In stock | $ 150.00 | |
10 mg | In stock | $ 207.00 | |
25 mg | In stock | $ 347.00 | |
50 mg | In stock | $ 515.00 | |
100 mg | In stock | $ 747.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 197.00 |
Description | Cintirorgon (LYC-55716) is a selective, oral agonist of RORγ. Cintirorgon modulates gene expression of RORγ expressing T lymphocyte immune cells. |
In vitro | Upon oral administration of Cintirorgon, this agent selectively binds to the nuclear receptor transcription factor RORγ, forming a receptor complex that translocates to the nucleus, and binds to ROR response elements (ROREs), enhancing the function, proliferation and survival of type 17 T cells, including Th17 (helper T cells) and Tc17 (cytotoxic T cells). RORγ, the nuclear receptor transcription factor that is involved in Th17/Tc17 differentiation, plays a key role in immune activation. |
Synonyms | LYC-55716 |
Molecular Weight | 603.53 |
Formula | C27H23F6NO6S |
CAS No. | 2055536-64-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 110 mg/mL (182.26 mM)
You can also refer to dose conversion for different animals. More
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Cintirorgon 2055536-64-4 Metabolism ROR inhibit LYC55716 LYC 55716 RAR-related orphan receptor LYC-55716 Inhibitor inhibitor