Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GSA-10 is a potent Smoothened (Smo) receptor agonist with an EC50 of 1.2 μM. It acts on Smo to promote the differentiation of pluripotent mesenchymal stem cells into osteoblasts. It also mediates Hedgehog (Hh) signaling, which may have research implications for regenerative medicine in cancer diseases.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 135.00 | |
2 mg | In stock | $ 197.00 | |
5 mg | In stock | $ 313.00 | |
10 mg | In stock | $ 468.00 | |
25 mg | In stock | $ 753.00 | |
50 mg | In stock | $ 987.00 | |
100 mg | In stock | $ 1,390.00 |
Description | GSA-10 is a potent Smoothened (Smo) receptor agonist with an EC50 of 1.2 μM. It acts on Smo to promote the differentiation of pluripotent mesenchymal stem cells into osteoblasts. It also mediates Hedgehog (Hh) signaling, which may have research implications for regenerative medicine in cancer diseases. |
Targets&IC50 | Smo receptor:1.2 μM(EC50) |
Molecular Weight | 450.53 |
Formula | C26H30N2O5 |
CAS No. | 300833-95-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Insoluble
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
GSA-10 300833-95-8 GPCR/G Protein Stem Cells Hedgehog/Smoothened Inhibitor differentiation regenerative medicine Smoothened receptor quinolinecarboxamide derivative GSA 10 cancer Smoothened GSA10 Smo osteoblasts Hedgehog inhibit multipotent mesenchymal progenitor cell inhibitor