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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $39 | In Stock | |
10 mg | $48 | In Stock | |
25 mg | $97 | In Stock | |
50 mg | $172 | In Stock | |
100 mg | $320 | In Stock | |
200 mg | $478 | In Stock | |
500 mg | $772 | In Stock | |
1 mL x 10 mM (in DMSO) | $43 | In Stock |
Description | IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S can reduce inflammation and cartilage loss associated with CIA and can serve as a small-molecule modulator for mechanistic studies of JNK function in rheumatoid arthritis. IQ-1S is highly specific for JNK and that its neutral form is the most abundant species at physiologic pH. |
Targets&IC50 | NF-κB:2.3±0.41 μM |
Alias | IQ-1, IQ-1S, IQ-1S (free acid) |
Molecular Weight | 247.25 |
Formula | C15H9N3O |
Cas No. | 23146-22-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 18.33 mg/mL (74.15 mM), Sonication is recommended. ![]() | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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