Powder: -20°C for 3 years | In solvent: -80°C for 1 year
IQ3 is a selective inhibitor of JNK3(JNK3, JNK1 and JNK2 with Kd of 66 nM, 240 nM and 290 nM, respectively). IQ 3 inhibits NF-κB/AP1 transcriptional activity in THP1-Blue cells with IC50 of 1.4 μM, also inhibits TNF-α and IL-6 production in vitro.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
5 mg | In stock | $ 77.00 | |
10 mg | In stock | $ 117.00 | |
25 mg | In stock | $ 231.00 | |
50 mg | In stock | $ 369.00 | |
100 mg | In stock | $ 549.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 88.00 |
Description | IQ3 is a selective inhibitor of JNK3(JNK3, JNK1 and JNK2 with Kd of 66 nM, 240 nM and 290 nM, respectively). IQ 3 inhibits NF-κB/AP1 transcriptional activity in THP1-Blue cells with IC50 of 1.4 μM, also inhibits TNF-α and IL-6 production in vitro. |
Targets&IC50 | JNK3:66 nM(Kd) , JNK1:240 nM(Kd) , JNK2:290 nM(Kd) |
Molecular Weight | 341.32 |
Formula | C20H11N3O3 |
CAS No. | 312538-03-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3.41 mg/mL (10 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
IQ-3 312538-03-7 MAPK JNK Inhibitor IL-6 inhibit TNF-α IQ3 IQ 3 IL-1β IL-1α inhibitor