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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $31 | In Stock | |
2 mg | $44 | In Stock | |
5 mg | $72 | In Stock | |
10 mg | $122 | In Stock | |
25 mg | $222 | In Stock | |
50 mg | $372 | In Stock | |
100 mg | $556 | In Stock | |
1 mL x 10 mM (in DMSO) | $79 | In Stock |
Description | IRAK4-IN-7 (CA-4948) is a selective and potent IRAK4 kinase inhibitor with in vivo activity in a TLR4-induced cytokine release model. |
In vitro | CA-4948 was previously shown to exhibit dose-dependent efficacy in ABC-DLBCL MYD88-L265P xenograft tumor models using cell lines OCI-LY3 and OCI-LY10[1]. |
In vivo | CA-4948 has antitumor activity in ABC-type diffuse large B cell lymphoma patient-derived xenograft (PDX) mouse models[2]. |
Alias | CA-4948 |
Molecular Weight | 417.42 |
Formula | C21H19N7O3 |
Cas No. | 1801343-74-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 13.89 mg/mL (33.28 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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