Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 33.00 | |
2 mg | In stock | $ 45.00 | |
5 mg | In stock | $ 64.00 | |
10 mg | In stock | $ 100.00 | |
25 mg | In stock | $ 211.00 | |
50 mg | In stock | $ 297.00 | |
100 mg | In stock | $ 415.00 | |
500 mg | In stock | $ 983.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 80.00 |
Description | ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM). |
Targets&IC50 | Rab7:77.6 nM (EC50) |
In vitro | ML098 (CID-7345532) functions by increasing the affinity of the GTPases for guanine nucleotides, leading to the hypothesis that these activators interact with GTPases bind to an allosteric binding site localized between switch regions I and II. ML-098 is an activator of the GTP-binding protein Rab7 with an EC50 of 77.6 nM which shows selectivity against the related GTPases cdc42, Ras, Rab-2A, and Rac1 (EC50s = 588.8, 346.7, 158.5, and 794.3 nM, respectively)[1]. |
Synonyms | CID-7345532 |
Molecular Weight | 309.36 |
Formula | C19H19NO3 |
CAS No. | 878978-76-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (161.6 mM)
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ML-098 878978-76-8 GPCR/G Protein MAPK Ras inhibit ML 098 Inhibitor CID 7345532 CID-7345532 CID7345532 ML098 inhibitor