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Moracin C

Catalog No. TN1949Cas No. 69120-06-5

Moracin C, a natural compound found in Morus mesozygia, Morus alba var. multicaulis, is an anti-inflammatory agent. moracin C inhibits nitric oxide (NO) release and LPS-activated reactive oxygen species (ROS) in cells.

Moracin C

Moracin C

Purity: 99.86%
Catalog No. TN1949Cas No. 69120-06-5
Moracin C, a natural compound found in Morus mesozygia, Morus alba var. multicaulis, is an anti-inflammatory agent. moracin C inhibits nitric oxide (NO) release and LPS-activated reactive oxygen species (ROS) in cells.
Pack SizePriceAvailabilityQuantity
1 mg$1988-10 weeks
5 mg$5138-10 weeks
10 mg$7478-10 weeks
25 mg$1,1608-10 weeks
50 mg$1,5608-10 weeks
100 mg$2,0808-10 weeks
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Purity:99.86%
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Product Introduction

Bioactivity
Description
Moracin C, a natural compound found in Morus mesozygia, Morus alba var. multicaulis, is an anti-inflammatory agent. moracin C inhibits nitric oxide (NO) release and LPS-activated reactive oxygen species (ROS) in cells.
Targets&IC50
FabI (S. aureus):83.8 µM, S. aureus:32 µg/mL(MIC)
In vitro
Moracin C (1-50 μM, 24 h) inhibited the release of LPS-activated reactive oxygen species (ROS) and nitric oxide (NO) from RAW264.7 cells.[2]
Moracin C (1-50 μM, 2 h) inhibits mRNA and protein expression of iNOS and COX-2 in RAW264.7 cells.[2]
Moracin C (1-50 μM, 2 h) inhibits the production of pro-inflammatory cytokines (IL-1β, IL-6 and TNF-α) in LPS-activated RAW 264.7 cells [1].
Moracin C (1-50 μM, 2 h) inhibits the phosphorylation of p38, ERK and JNK in LPS-activated RAW 264.7 cells.[2]
In vivo
Moracin C (100 mg/kg, gavage, mice) is rapidly and well absorbed in the intestinal tract and is widely distributed in the gastrointestinal tract, liver, kidney and lungs.[3]
Chemical Properties
Molecular Weight310.34
FormulaC19H18O4
Cas No.69120-06-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 225.0 mg/mL (725.0 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.2223 mL16.1114 mL32.2227 mL161.1136 mL
5 mM0.6445 mL3.2223 mL6.4445 mL32.2227 mL
10 mM0.3222 mL1.6111 mL3.2223 mL16.1114 mL
20 mM0.1611 mL0.8056 mL1.6111 mL8.0557 mL
50 mM0.0644 mL0.3222 mL0.6445 mL3.2223 mL
100 mM0.0322 mL0.1611 mL0.3222 mL1.6111 mL

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