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Moracin C, a natural compound found in Morus mesozygia, Morus alba var. multicaulis, is an anti-inflammatory agent. moracin C inhibits nitric oxide (NO) release and LPS-activated reactive oxygen species (ROS) in cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $198 | 8-10 weeks | |
5 mg | $513 | 8-10 weeks | |
10 mg | $747 | 8-10 weeks | |
25 mg | $1,160 | 8-10 weeks | |
50 mg | $1,560 | 8-10 weeks | |
100 mg | $2,080 | 8-10 weeks |
Description | Moracin C, a natural compound found in Morus mesozygia, Morus alba var. multicaulis, is an anti-inflammatory agent. moracin C inhibits nitric oxide (NO) release and LPS-activated reactive oxygen species (ROS) in cells. |
Targets&IC50 | FabI (S. aureus):83.8 µM, S. aureus:32 µg/mL(MIC) |
In vitro | Moracin C (1-50 μM, 24 h) inhibited the release of LPS-activated reactive oxygen species (ROS) and nitric oxide (NO) from RAW264.7 cells.[2] Moracin C (1-50 μM, 2 h) inhibits mRNA and protein expression of iNOS and COX-2 in RAW264.7 cells.[2] Moracin C (1-50 μM, 2 h) inhibits the production of pro-inflammatory cytokines (IL-1β, IL-6 and TNF-α) in LPS-activated RAW 264.7 cells [1]. Moracin C (1-50 μM, 2 h) inhibits the phosphorylation of p38, ERK and JNK in LPS-activated RAW 264.7 cells.[2] |
In vivo | Moracin C (100 mg/kg, gavage, mice) is rapidly and well absorbed in the intestinal tract and is widely distributed in the gastrointestinal tract, liver, kidney and lungs.[3] |
Molecular Weight | 310.34 |
Formula | C19H18O4 |
Cas No. | 69120-06-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 225.0 mg/mL (725.0 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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