Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significantly reduce the expression of CDK1-inhibitory kinases, Myt1 and Wee1, and cause cyclin B1 protein accumulation leading to CDK1 activation in T24 cells. 3. Flavokawain A (Flavokavain A) may exert anti-inflammatory responses by suppressing LPS-induced expression of pro-inflammatory mediators via blockage of NF-κB-AP-1-JNK/p38 MAPK signaling pathways in the murine macrophages.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 42.00 | |
100 mg | In stock | $ 66.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 46.00 |
Description | NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significantly reduce the expression of CDK1-inhibitory kinases, Myt1 and Wee1, and cause cyclin B1 protein accumulation leading to CDK1 activation in T24 cells. 3. Flavokawain A (Flavokavain A) may exert anti-inflammatory responses by suppressing LPS-induced expression of pro-inflammatory mediators via blockage of NF-κB-AP-1-JNK/p38 MAPK signaling pathways in the murine macrophages. |
Source |
Synonyms | Flavokavain A |
Molecular Weight | 314.33 |
Formula | C18H18O5 |
CAS No. | 3420-72-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 29 mg/mL(92.3 mM)
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble
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Flavokawain A 3420-72-2 Apoptosis MAPK p38 MAPK EJ cells T24 anticarcinogenic inhibit Inhibitor chalcone Apoptotic bladder cancer Flavokavain A tumor inhibitor