Shopping Cart

Remove All

Your shopping cart is currently empty

Flavokawain A

Select Batch

Purity:99.72%

Resource Download

COA HNMR HPLC

Flavokawain A

Catalog No. T3S0737Cas No. 3420-72-2

NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significantly reduce the expression of CDK1-inhibitory kinases, Myt1 and Wee1, and cause cyclin B1 protein accumulation leading to CDK1 activation in T24 cells. 3. Flavokawain A (Flavokavain A) may exert anti-inflammatory responses by suppressing LPS-induced expression of pro-inflammatory mediators via blockage of NF-κB-AP-1-JNK/p38 MAPK signaling pathways in the murine macrophages.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
50 mg	$42	In Stock
100 mg	$66	In Stock
1 mL x 10 mM (in DMSO)	$46	In Stock

Bulk & Custom

Add to Cart

Questions

Related Compound Libraries of "Flavokawain A"

Product Introduction

Bioactivity

Description

Alias

Flavokavain A

Chemical Properties

Molecular Weight	314.33
Formula	C18H18O5
Cas No.	3420-72-2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/mL (174.98 mM)

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1814 mL	15.9068 mL	31.8137 mL	159.0685 mL
5 mM	0.6363 mL	3.1814 mL	6.3627 mL	31.8137 mL
10 mM	0.3181 mL	1.5907 mL	3.1814 mL	15.9068 mL
20 mM	0.1591 mL	0.7953 mL	1.5907 mL	7.9534 mL
50 mM	0.0636 mL	0.3181 mL	0.6363 mL	3.1814 mL
100 mM	0.0318 mL	0.1591 mL	0.3181 mL	1.5907 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc