store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NV-5138 is a selective and orally active activator of brain mTORC1, with antidepressant effects.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 91.00 | |
5 mg | In stock | $ 226.00 | |
10 mg | In stock | $ 363.00 | |
25 mg | In stock | $ 776.00 | |
50 mg | In stock | $ 1,230.00 | |
100 mg | In stock | $ 1,780.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 178.00 |
Description | NV-5138 is a selective and orally active activator of brain mTORC1, with antidepressant effects. |
In vivo | NV-5138 (160 mg/kg, po, single dose) rapidly increases levels of phospho-mTOR as well as the downstream targets, phospho-p70S6K1, and phosphor-4EB-P1, in synaptosomal preparations of PFC[2].?NV-5138 (80 mg/kg, po, daily for a total of 7 days) also produces antidepressant effects[2]. |
Molecular Weight | 181.18 |
Formula | C7H13F2NO2 |
CAS No. | 2095886-80-7 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 1.81 mg/ml (10 mM)
You can also refer to dose conversion for different animals. More
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NV-5138 2095886-80-7 PI3K/Akt/mTOR signaling mTOR inhibit Inhibitor NV5138 Mammalian target of Rapamycin NV 5138 inhibitor