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Nitrocaramiphen hydrochloride

Nitrocaramiphen hydrochloride
Nitrocaramiphen hydrochloride, a selective M1 muscarinic antagonist, inhibits binding to sigma sites in the brain.
Catalog No. T23071Cas No. 98636-73-8
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Purity:98.94%
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Nitrocaramiphen hydrochloride

Catalog No. T23071Cas No. 98636-73-8
Nitrocaramiphen hydrochloride, a selective M1 muscarinic antagonist, inhibits binding to sigma sites in the brain.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
5 mg$43In Stock
10 mg$68In Stock
25 mg$137In Stock
50 mg$223In Stock
100 mg$329In Stock
200 mg$470In Stock
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Product Introduction

Bioactivity
Description
Nitrocaramiphen hydrochloride, a selective M1 muscarinic antagonist, inhibits binding to sigma sites in the brain.
Targets&IC50
M1:5.5 nM(Ki)
In vitro
Nitrocaramiphen hydrochloride binds with high affinity for M1 sites (Ki = 5.5 nM) and with a 71-fold selectivity over M2, and a 10-fold selectivity for the M1 over the M3 subtype[1].?
Chemical Properties
Molecular Weight370.87
FormulaC18H27ClN2O4
Cas No.98636-73-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 10 mM
DMSO: 3.71 mg/mL (10 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM2.6964 mL13.4818 mL26.9636 mL134.8181 mL
5 mM0.5393 mL2.6964 mL5.3927 mL26.9636 mL
10 mM0.2696 mL1.3482 mL2.6964 mL13.4818 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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Dose Conversion

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