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Rutin

Catalog No. T0795 CAS 153-18-4

Synonyms: Quercetin 3-O-rutinoside, Rutoside

Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Rutin, CAS 153-18-4

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500 mg	In stock	$ 36.00

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Purity: 97.19%

Purity: 95%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.
In vitro	The intraperitoneal injection in mice has determined the median lethal dose (LD50) of Rutin to be 650 mg/kg.
In vivo	Rutin inhibits platelet aggregation and diminishes capillary permeability, thinning the blood and enhancing circulation. Consequently, Rutin may prevent blood clot formation and is utilized in treating heart disease and stroke.
Source	Natural Products > Rutaceae > Ruta

Synonyms	Quercetin 3-O-rutinoside, Rutoside
Molecular Weight	610.52
Formula	C27H30O16
CAS No.	153-18-4

Storage

store at low temperature,store under nitrogen

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 122 mg/mL (199.82 mM)

Ethanol: 2 mg/mL (3.27 mM)

References and Literature

1. Navarro-Nunez L, et al. J Agric Food Chem, 2008, 56(9), 2970-2976. 2. Ortolani O, et al. Transplant Proc, 1995, 27(5), 2877-2878. 3. Liang Y, Xu Z, Wu X, et al. Inhibition of hyperpolarization-activated cyclic nucleotide-gated channels with natural flavonoid quercetin[J]. Biochemical and Biophysical Research Communications. 2020 4. Shim K S, Hwang Y H, Jang S A, et al. Ethanol Extract of Amomum tsao-ko Ameliorates Ovariectomy-Induced Trabecular Loss and Fat Accumulation[J]. Molecules. 2021, 26(4): 784.

Citations

1. Jang S A, Hwang Y H, Yang H, et al. Water Extract of Mentha arvensis L. Attenuates Estrogen Deficiency-Induced Bone Loss by Inhibiting Osteoclast Differentiation. Frontiers in Pharmacology. 2021, 12. 2. Ding H, Li Y, Zhao C, et al. Rutin Supplementation Reduces Oxidative Stress, Inflammation and Apoptosis of Mammary Gland in Sheep During the Transition Period. Frontiers in Veterinary Science. 2022.9 3. Shim K S, Hwang Y H, Jang S A, et al. Ethanol Extract of Amomum tsao-ko Ameliorates Ovariectomy-Induced Trabecular Loss and Fat Accumulation. Molecules. 2021 Feb 3;26(4):784. doi: 10.3390/molecules26040784. 4. Liang Y, Xu Z, Wu X, et al. Inhibition of hyperpolarization-activated cyclic nucleotide-gated channels with natural flavonoid quercetin. Biochemical and Biophysical Research Communications. 2020

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Clinical Compound Library Anti-Neurodegenerative Disease Compound Library Anti-Cancer Drug Library Antiparasitic Natural Product Library Anti-Cancer Approved Drug Library Anti-Cancer Active Compound Library Microbial Natural Product Library Drug Repurposing Compound Library Tobacco Monomer Library GPCR Compound Library

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Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Keywords

Rutin 153-18-4 Autophagy GPCR/G Protein Immunology/Inflammation Neuroscience Beta Amyloid Prostaglandin Receptor Amyloid-β neuroprotective Quercetin 3-O-rutinoside brain nephroprotective antioxidant blood barrier β-amyloid peptide Rutoside anti-inflammatory Abeta inhibit Inhibitor flavonoid hepatoprotective antidiabetic inhibitor

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