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SIBA

Catalog No. T12908Cas No. 35899-54-8
Alias 5'-Isobutylthioadenosine, 5'-Deoxy-5'-isobutylthioadenosine

SIBA (5'-Deoxy-5'-isobutylthioadenosine) is a synthetic analogue of SAH, acts as an inhibitor of S-adenosylmethionine-mediated transmethylation. SIBA can interfere with a variety of enzymatic activities in vitro, such as SAH hydrolase, methylthioadenosine phosphorylase and cAMP phosphodiesterase. SIBA reversibly blocks the multiplication of herpes simplex type 1 virus (HSV)

SIBA

SIBA

Purity: 99.48%
Catalog No. T12908Alias 5'-Isobutylthioadenosine, 5'-Deoxy-5'-isobutylthioadenosineCas No. 35899-54-8
SIBA (5'-Deoxy-5'-isobutylthioadenosine) is a synthetic analogue of SAH, acts as an inhibitor of S-adenosylmethionine-mediated transmethylation. SIBA can interfere with a variety of enzymatic activities in vitro, such as SAH hydrolase, methylthioadenosine phosphorylase and cAMP phosphodiesterase. SIBA reversibly blocks the multiplication of herpes simplex type 1 virus (HSV)
Pack SizePriceAvailabilityQuantity
1 mg$44In Stock
5 mg$95In Stock
10 mg$119In Stock
25 mg$231In Stock
50 mg$346In Stock
100 mg$493In Stock
200 mg$687In Stock
1 mL x 10 mM (in DMSO)$106In Stock
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Purity:99.48%
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Product Introduction

Bioactivity
Description
SIBA (5'-Deoxy-5'-isobutylthioadenosine) is a synthetic analogue of SAH, acts as an inhibitor of S-adenosylmethionine-mediated transmethylation. SIBA can interfere with a variety of enzymatic activities in vitro, such as SAH hydrolase, methylthioadenosine phosphorylase and cAMP phosphodiesterase. SIBA reversibly blocks the multiplication of herpes simplex type 1 virus (HSV)
Alias5'-Isobutylthioadenosine, 5'-Deoxy-5'-isobutylthioadenosine
Chemical Properties
Molecular Weight339.41
FormulaC14H21N5O3S
Cas No.35899-54-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 90 mg/mL (265.17 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9463 mL14.7314 mL29.4629 mL147.3145 mL
5 mM0.5893 mL2.9463 mL5.8926 mL29.4629 mL
10 mM0.2946 mL1.4731 mL2.9463 mL14.7314 mL
20 mM0.1473 mL0.7366 mL1.4731 mL7.3657 mL
50 mM0.0589 mL0.2946 mL0.5893 mL2.9463 mL
100 mM0.0295 mL0.1473 mL0.2946 mL1.4731 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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