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Sigma-1 receptor antagonist 3

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Catalog No. T12912Cas No. 1639220-17-9

Sigma-1 receptor antagonist 3 is a more potent and selective antagonist of Sigma-1 (σ1) receptor (Ki = 1.14 nM) than σ2 receptor(Ki = 1239 nM). Sigma-1 receptor antagonist 3 inhibits Human Ether-a-go-go-Related Gene (hERG, IC50 = 1.54 μM)

Sigma-1 receptor antagonist 3

Sigma-1 receptor antagonist 3

🥰Excellent
Purity: 100%
Catalog No. T12912Cas No. 1639220-17-9
Sigma-1 receptor antagonist 3 is a more potent and selective antagonist of Sigma-1 (σ1) receptor (Ki = 1.14 nM) than σ2 receptor(Ki = 1239 nM). Sigma-1 receptor antagonist 3 inhibits Human Ether-a-go-go-Related Gene (hERG, IC50 = 1.54 μM)
Pack SizePriceAvailabilityQuantity
1 mg$81In Stock
5 mg$197In Stock
10 mg$322In Stock
25 mg$529In Stock
50 mg$718In Stock
100 mg$953In Stock
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Product Introduction

Bioactivity
Description
Sigma-1 receptor antagonist 3 is a potent and selective antagonist of Sigma-1 (σ1) receptor(Ki : 1.14 nM), has the potential for the neuropathic pain.
Targets&IC50
σ1 receptor:1.14 nM nM(Ki), ERG (human):1.54 μM , σ2 receptor:1239 nM(Ki)
Chemical Properties
Molecular Weight363.86
FormulaC19H23ClFN3O
Cas No.1639220-17-9
SmilesCc1nc(nc(OCCCN2CCCCC2)c1Cl)-c1ccc(F)cc1
Relative Density.1.196 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: <1 mg/mL (insoluble or slightly soluble), Sonication is recommended.

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