Powder: -20°C for 3 years | In solvent: -80°C for 1 year
XCT790 is a potent, selective and inverse agonist of estrogen-related receptor alpha(ERRα).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 59.00 | |
10 mg | In stock | $ 98.00 | |
25 mg | In stock | $ 189.00 | |
50 mg | In stock | $ 345.00 | |
100 mg | In stock | $ 513.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 79.00 |
Description | XCT790 is a potent, selective and inverse agonist of estrogen-related receptor alpha(ERRα). |
Targets&IC50 | ERRα:0.37 μM (IC50) |
Kinase Assay | The inhibition of SHP2 from the tested compounds (SHP099) concentrations varying from 0.003-100 μM is monitored using an assay in which 0.5 nM of SHP2 is incubated with of 0.5 μM of peptide IRS1_pY1172(dPEG8)pY1222. After 30-60 minutes incubation at the surrogate substrate, DiFMUP is added to the reaction and incubated at 25 °C for 30 minutes. The reaction is then quenched by the addition of 5 μL of a 160 μM solution of bpV(Phen). The fluorescence signal is monitored using a microplate reader using excitation and emission wavelengths of 340 nm and 450 nm, respectively[1]. |
Molecular Weight | 596.42 |
Formula | C23H13F9N4O3S |
CAS No. | 725247-18-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 21 mg/mL (35.21 mM), Sonication and heating are recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
XCT790 725247-18-7 Autophagy Endocrinology/Hormones Estrogen Receptor/ERR Estrogen/progestogen Receptor XCT 790 Inhibitor XCT-790 inhibit inhibitor