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AA26-9 is an effective and broad-spectrum inhibitor of serine hydrolase.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $31 | In Stock | |
2 mg | $44 | In Stock | |
5 mg | $72 | In Stock | |
10 mg | $122 | In Stock | |
25 mg | $222 | In Stock | |
50 mg | $369 | In Stock | |
100 mg | $549 | In Stock | |
1 mL x 10 mM (in DMSO) | $79 | In Stock |
Description | AA26-9 is an effective and broad-spectrum inhibitor of serine hydrolase. |
In vitro | AA26-9 inhibits enzymes originated from diverse functional subclasses of serine hydrolases, including peptidases (APEH, CTSA, PRCP), thioesterases (LYPLA1/2), lipases/phospholipases (AADACL1, ESD, ABHD6, PAFAH2, FAAH, LYPLA3), and uncharacterized enzymes (ABHD11, ABHD13, BAT5). AA26-9 inhibits 1/3 of the over 40 serine hydrolase found in T-cells. |
Cell Research | AA26-9 is prepared in DMSO. Cells are cultured with 20 μM inhibitor AA26-9 or DMSO as a control for 4 h, lysed, separated into soluble and analyzed by competitive gel-based ABPP[1]. |
Molecular Weight | 166.18 |
Formula | C7H10N4O |
Cas No. | 1312782-34-5 |
Smiles | O=C(N1CCCC1)n1ccnn1 |
Relative Density. | 1.42 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 55 mg/mL (330.96 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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