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AA26-9

🥰Excellent
Catalog No. T3990Cas No. 1312782-34-5

AA26-9 is an effective and broad-spectrum inhibitor of serine hydrolase.

AA26-9

AA26-9

🥰Excellent
Purity: 100%
Catalog No. T3990Cas No. 1312782-34-5
AA26-9 is an effective and broad-spectrum inhibitor of serine hydrolase.
Pack SizePriceAvailabilityQuantity
1 mg$31In Stock
2 mg$44In Stock
5 mg$72In Stock
10 mg$122In Stock
25 mg$222In Stock
50 mg$369In Stock
100 mg$549In Stock
1 mL x 10 mM (in DMSO)$79In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
AA26-9 is an effective and broad-spectrum inhibitor of serine hydrolase.
In vitro
AA26-9 inhibits enzymes originated from diverse functional subclasses of serine hydrolases, including peptidases (APEH, CTSA, PRCP), thioesterases (LYPLA1/2), lipases/phospholipases (AADACL1, ESD, ABHD6, PAFAH2, FAAH, LYPLA3), and uncharacterized enzymes (ABHD11, ABHD13, BAT5). AA26-9 inhibits 1/3 of the over 40 serine hydrolase found in T-cells.
Cell Research
AA26-9 is prepared in DMSO. Cells are cultured with 20 μM inhibitor AA26-9 or DMSO as a control for 4 h, lysed, separated into soluble and analyzed by competitive gel-based ABPP[1].
Chemical Properties
Molecular Weight166.18
FormulaC7H10N4O
Cas No.1312782-34-5
SmilesO=C(N1CCCC1)n1ccnn1
Relative Density.1.42 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (330.96 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM6.0176 mL30.0879 mL60.1757 mL300.8786 mL
5 mM1.2035 mL6.0176 mL12.0351 mL60.1757 mL
10 mM0.6018 mL3.0088 mL6.0176 mL30.0879 mL
20 mM0.3009 mL1.5044 mL3.0088 mL15.0439 mL
50 mM0.1204 mL0.6018 mL1.2035 mL6.0176 mL
100 mM0.0602 mL0.3009 mL0.6018 mL3.0088 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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