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AChE/BChE-IN-10

Catalog No. T61969Cas No. 2924824-48-4

AChE/BChE-IN-10 is a potent dual inhibitor of AChE and BChE with IC50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 exhibits good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation.

AChE/BChE-IN-10

AChE/BChE-IN-10

Purity: 99.75%
Catalog No. T61969Cas No. 2924824-48-4
AChE/BChE-IN-10 is a potent dual inhibitor of AChE and BChE with IC50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 exhibits good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation.
Pack SizePriceAvailabilityQuantity
5 mg$39In Stock
10 mg$65In Stock
25 mg$136In Stock
50 mg$223In Stock
100 mg$323In Stock
500 mgInquiryIn Stock
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Purity:99.75%
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Product Introduction

Bioactivity
Description
AChE/BChE-IN-10 is a potent dual inhibitor of AChE and BChE with IC50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 exhibits good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation.
Targets&IC50
AChE:0.176 μM, BChE:0.47 μM
In vitro
AChE/BChE-IN-10 inhibits AChE non-competitively (Ki = 0.21 μM) and BChE via mixed inhibition (Ki = 0.15 μM) [1].
Chemical Properties
Molecular Weight402.53
FormulaC26H30N2O2
Cas No.2924824-48-4
Storage & Solubility Information
Storagestore at low temperature | Shipping with blue ice.
Solubility Information
DMSO: 4.03 mg/mL (10 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4843 mL12.4214 mL24.8429 mL124.2143 mL
5 mM0.4969 mL2.4843 mL4.9686 mL24.8429 mL
10 mM0.2484 mL1.2421 mL2.4843 mL12.4214 mL

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