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AChE/BChE-IN-10 is a potent dual inhibitor of AChE and BChE with IC50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 exhibits good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $39 | In Stock | |
10 mg | $65 | In Stock | |
25 mg | $136 | In Stock | |
50 mg | $223 | In Stock | |
100 mg | $323 | In Stock | |
500 mg | Inquiry | In Stock |
Description | AChE/BChE-IN-10 is a potent dual inhibitor of AChE and BChE with IC50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 exhibits good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation. |
Targets&IC50 | AChE:0.176 μM, BChE:0.47 μM |
In vitro | AChE/BChE-IN-10 inhibits AChE non-competitively (Ki = 0.21 μM) and BChE via mixed inhibition (Ki = 0.15 μM) [1]. |
Molecular Weight | 402.53 |
Formula | C26H30N2O2 |
Cas No. | 2924824-48-4 |
Smiles | O=C(NCCC1CCN(CC=2C=CC=CC2)CC1)C3=CC=C4C=C(OC)C=CC4=C3 |
Relative Density. | no data available |
Storage | store at low temperature | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | DMSO: 4.03 mg/mL (10 mM) | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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