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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $89 | In Stock | |
2 mg | $125 | In Stock | |
5 mg | $197 | In Stock | |
10 mg | $322 | In Stock | |
25 mg | $569 | In Stock | |
50 mg | $823 | In Stock | |
100 mg | $1,230 | In Stock |
Description | Bemnifosbuvir hemisulfate (AT-527) is a potent inhibitor of HCV virus replication. |
In vitro | The potent in vitro activity of AT-511, the free base of bemnifosbuvir hemisulfate, against several coronaviruses, including SARS-CoV-2. In normal human airway epithelial cells, the concentration of AT-511 required to inhibit replication of SARS-CoV-2 by 90% (EC90) was 0.47?μM, very similar to its EC90 against human coronavirus (HCoV)-229E, HCoV-OC43, and SARS-CoV in Huh-7 cells[1]. |
In vivo | When given orally to rats and monkeys, bemnifosbuvir hemisulfate preferentially delivered high levels of AT-9010 in the liver in vivo.These favorable preclinical attributes support bemnifosbuvir hemisulfate may increase SVR rates[2]. |
Alias | AT-527 |
Molecular Weight | 1261.15 |
Formula | C48H68F2N14O18P2S |
Cas No. | 2241337-84-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 170 mg/mL (269.60 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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