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Boc-Asp(OMe)-fluoromethyl ketone
🥰Excellent
Catalog No. T39308Cas No. 187389-53-3
Alias Boc-Asp(OMe)-FMK, Boc-Asp(OMe)-fluoromethyl ketone
Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) is a broad range caspase inhibitor. Boc-Asp(OME)-Fluoromethyl Ketone inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8.
Boc-Asp(OMe)-fluoromethyl ketone
🥰Excellent
Catalog No. T39308Alias Boc-Asp(OMe)-FMK, Boc-Asp(OMe)-fluoromethyl ketoneCas No. 187389-53-3
Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) is a broad range caspase inhibitor. Boc-Asp(OME)-Fluoromethyl Ketone inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 38 € | In Stock | |
| 5 mg | 92 € | In Stock | |
| 10 mg | 147 € | In Stock | |
| 25 mg | 297 € | In Stock | |
| 50 mg | 468 € | In Stock | |
| 100 mg | 686 € | In Stock | |
| 1 mL x 10 mM (in DMSO) | 89 € | In Stock |
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) is a broad range caspase inhibitor. Boc-Asp(OME)-Fluoromethyl Ketone inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8. |
| In vitro | Boc-Asp(OME)-Fluoromethyl Keton (100 μM; 30 minutes; Polymorphonuclear leukocytes) prevents Fas-induced and spontaneous apoptosis (-CH-11)[1], and at 20 μM for 5 hours in J774.1/JA-4 cells, it significantly increases the release of LDH[2]. |
| Alias | Boc-Asp(OMe)-FMK, Boc-Asp(OMe)-fluoromethyl ketone |
| Molecular Weight | 263.26 |
| Formula | C11H18FNO5 |
| Cas No. | 187389-53-3 |
| Smiles | [C@H](NC(OC(C)(C)C)=O)(CC(OC)=O)C(CF)=O |
| Relative Density. | 1.150 g/cm3 at 20℃ |
Storage & Solubility Information
| Storage | keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 60 mg/mL (227.91 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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