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Briciclib

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Catalog No. T3207Cas No. 865783-99-9
Alias ON 014185

Briciclib (ON 014185) is a small molecule that inhibits cyclin D1 accumulation in Y cells.

Briciclib

Briciclib

🥰Excellent
Purity: 99.84%
Catalog No. T3207Alias ON 014185Cas No. 865783-99-9
Briciclib (ON 014185) is a small molecule that inhibits cyclin D1 accumulation in Y cells.
Pack SizePriceAvailabilityQuantity
1 mg$39In Stock
2 mg$52In Stock
5 mg$80In Stock
10 mg$128In Stock
25 mg$263In Stock
50 mg$396In Stock
100 mg$589In Stock
500 mg$1,280In Stock
1 mL x 10 mM (in DMSO)$89In Stock
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Purity:99.84%
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Product Introduction

Bioactivity
Description
Briciclib (ON 014185) is a small molecule that inhibits cyclin D1 accumulation in Y cells.
AliasON 014185
Chemical Properties
Molecular Weight474.42
FormulaC19H23O10PS
Cas No.865783-99-9
SmilesC(=C/S(CC1=CC(OP(=O)(O)O)=C(OC)C=C1)(=O)=O)\C2=C(OC)C=C(OC)C=C2OC
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (105.39 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1078 mL10.5392 mL21.0784 mL105.3918 mL
5 mM0.4216 mL2.1078 mL4.2157 mL21.0784 mL
10 mM0.2108 mL1.0539 mL2.1078 mL10.5392 mL
20 mM0.1054 mL0.5270 mL1.0539 mL5.2696 mL
50 mM0.0422 mL0.2108 mL0.4216 mL2.1078 mL
100 mM0.0211 mL0.1054 mL0.2108 mL1.0539 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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