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Brivudine
🥰Excellent
Catalog No. T0718Cas No. 69304-47-8
Alias BVDU, Bromovinyldeoxyuridine
Brivudine (BVDU), an antiviral medicine, is used in the therapy of herpes zoster.
Brivudine
🥰Excellent
Purity: 99.4%
Catalog No. T0718Alias BVDU, BromovinyldeoxyuridineCas No. 69304-47-8
Brivudine (BVDU), an antiviral medicine, is used in the therapy of herpes zoster.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $39 | In Stock | |
| 50 mg | $55 | In Stock | |
| 100 mg | $72 | In Stock | |
| 200 mg | $98 | In Stock | |
| 500 mg | $158 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $43 | In Stock |
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Purity:99.4%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Brivudine (BVDU), an antiviral medicine, is used in the therapy of herpes zoster. |
| In vitro | Brivudine is an analog of thymidine, and is incorporated into the viral DNA. It blocks the action of DNA polymerases thereby inhibiting viral replication. It has a stronger antiviral effect against the varicella-zoster virus than reference compounds such as aciclovir or penciclovir[1]. It has high, selective activity against varicella zoster virus (VZV), inhibiting VZV replication, possibly through competitive inhibition of viral DNA polymerase, or by acting as an alternative substrate to deoxythymidine triphosphate, causing viral DNA strand breakage[2]. |
| In vivo | At a dose of 125 mg once daily, brivudine has been shown to be superior to aciclovir with respect to reducing the period of new blister production and shortening the duration of post-herpetic neuralgia[1]. |
| Alias | BVDU, Bromovinyldeoxyuridine |
| Molecular Weight | 333.14 |
| Formula | C11H13BrN2O5 |
| Cas No. | 69304-47-8 |
| Smiles | OC[C@H]1O[C@H](C[C@@H]1O)n1cc(\C=C\Br)c(=O)[nH]c1=O |
| Relative Density. | 1.7800 g/cm3 (Estimated) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (150.09 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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