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BZAD01

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BZAD01

Catalog No. T25196Cas No. 305339-41-7

BZAD01 is a selective NMDA NR1A/2B receptor antagonist.

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Pack Size	Price	Availability
1 mg	$34	In Stock
5 mg	$77	In Stock
10 mg	$127	In Stock
25 mg	$255	In Stock
50 mg	$397	In Stock
100 mg	$658	In Stock
500 mg	$1,360	In Stock
1 mL x 10 mM (in DMSO)	$108	In Stock

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Product Introduction

Bioactivity

Description	BZAD01 is a selective NMDA NR1A/2B receptor antagonist.
In vivo	Parkinsonism was induced by microinjection of the toxin, 6-hydroxydopamine (6-OHDA) into the medial forebrain bundle (MFB) of 40 Sprague-Dawley rats. Parkinsonism and the efficacy of drugs were assessed using a battery of behavioural tests including balance beam, apomorphine-induced rotation, body axis bias or "curling", head position bias and disengage sensorimotor latency test. The main effects were that BZAD01 co-administration prevented chronic levodopa-induced potentiation of apomorphine rotation. However levodopa-treated rats were slower than either controls or BZAD-01-treated rats in the locomotor test[2].
Alias	BZAD-01, BZAD 01

Chemical Properties

Molecular Weight	362.27
Formula	C16H12F6N2O
Cas No.	305339-41-7

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 55 mg/ml (151.82 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7604 mL	13.8019 mL	27.6037 mL	138.0186 mL
5 mM	0.5521 mL	2.7604 mL	5.5207 mL	27.6037 mL
10 mM	0.2760 mL	1.3802 mL	2.7604 mL	13.8019 mL
20 mM	0.1380 mL	0.6901 mL	1.3802 mL	6.9009 mL
50 mM	0.0552 mL	0.2760 mL	0.5521 mL	2.7604 mL
100 mM	0.0276 mL	0.1380 mL	0.2760 mL	1.3802 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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