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C6 Ceramide

Catalog No. T61884 CAS 124753-97-5

Synonyms: N-(hexanoyl)sphing-4-enine, N-hexanoylsphingosine

C6-ceramide is an activator of ceramide pathway and can play a role in a variety of cancer cell lines. As an adjuvant of chemotherapy agents, C6-ceramide can enhance the anti-tumor effect.

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C6 Ceramide, CAS 124753-97-5

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

C6-ceramide is an activator of ceramide pathway and can play a role in a variety of cancer cell lines. As an adjuvant of chemotherapy agents, C6-ceramide can enhance the anti-tumor effect.

Synonyms	N-(hexanoyl)sphing-4-enine, N-hexanoylsphingosine
Molecular Weight	397.644
Formula	C24H47NO3
CAS No.	124753-97-5

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 90.0 mg/mL (226.3 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Zhu Q, et, al. C6-ceramide synergistically potentiates the anti-tumor effects of histone deacetylase inhibitors via AKT dephosphorylation and α-tubulin hyperacetylation both in vitro and in vivo. Cell Death Dis. 2011 Jan 27;2(1):e117. 2. Liu L, et, al. C6-ceramide treatment inhibits the proangiogenic activity of multiple myeloma exosomes via the miR-29b/Akt pathway. J Transl Med. 2020 Aug 3;18(1):298.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

C6 Ceramide 124753-97-5 Apoptosis N-hexanoylsphingosine N-(hexanoyl)sphing-4-enine Inhibitor inhibitor inhibit

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