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CeMMEC13

Catalog No. T6801Cas No. 1790895-25-8

CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).

CeMMEC13

CeMMEC13

Purity: 97.95%
Catalog No. T6801Cas No. 1790895-25-8
CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).
Pack SizePriceAvailabilityQuantity
2 mg$39In Stock
5 mg$64In Stock
10 mg$113In Stock
25 mg$255In Stock
50 mg$463In Stock
100 mg$682In Stock
1 mL x 10 mM (in DMSO)$70In Stock
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Purity:97.95%
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Product Introduction

Bioactivity
Description
CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).
Targets&IC50
TAF1:2.1 μM
Chemical Properties
Molecular Weight336.34
FormulaC19H16N2O4
Cas No.1790895-25-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 6 mg/mL (17.83 mM)
DMSO: 62 mg/mL (184.3 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM2.9732 mL14.8659 mL29.7318 mL148.6591 mL
5 mM0.5946 mL2.9732 mL5.9464 mL29.7318 mL
10 mM0.2973 mL1.4866 mL2.9732 mL14.8659 mL
DMSO
1mg5mg10mg50mg
20 mM0.1487 mL0.7433 mL1.4866 mL7.4330 mL
50 mM0.0595 mL0.2973 mL0.5946 mL2.9732 mL
100 mM0.0297 mL0.1487 mL0.2973 mL1.4866 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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