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Dilmapimod

🥰Excellent
Catalog No. T12850Cas No. 444606-18-2
Alias SB-681323, GW 681323

Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK, potentially suppressing inflammation in chronic obstructive pulmonary disease.

Dilmapimod

Dilmapimod

🥰Excellent
Purity: 97.53%
Catalog No. T12850Alias SB-681323, GW 681323Cas No. 444606-18-2
Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK, potentially suppressing inflammation in chronic obstructive pulmonary disease.
Pack SizePriceAvailabilityQuantity
5 mg$39In Stock
10 mg$64In Stock
25 mg$122In Stock
50 mg$198In Stock
100 mg$369In Stock
1 mL x 10 mM (in DMSO)$43In Stock
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Purity:97.53%
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Product Introduction

Bioactivity
Description
Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK, potentially suppressing inflammation in chronic obstructive pulmonary disease.
In vitro
p38 MAPK signaling potently inhibited by Dilmapimod, measured by inhibition of sorbitol-induced pHSP27 expression.
AliasSB-681323, GW 681323
Chemical Properties
Molecular Weight456.42
FormulaC23H19F3N4O3
Cas No.444606-18-2
SmilesCc1cc(F)ccc1-c1nc(NC(CO)CO)nc2n(-c3c(F)cccc3F)c(=O)ccc12
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 125 mg/mL (273.87 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1910 mL10.9548 mL21.9096 mL109.5482 mL
5 mM0.4382 mL2.1910 mL4.3819 mL21.9096 mL
10 mM0.2191 mL1.0955 mL2.1910 mL10.9548 mL
20 mM0.1095 mL0.5477 mL1.0955 mL5.4774 mL
50 mM0.0438 mL0.2191 mL0.4382 mL2.1910 mL
100 mM0.0219 mL0.1095 mL0.2191 mL1.0955 mL

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