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Doramectin (Dectomax) is an antiparasitic agent.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $38 | In Stock | |
100 mg | $53 | In Stock | |
500 mg | $91 | In Stock | |
1 mL x 10 mM (in DMSO) | $50 | In Stock |
Description | Doramectin (Dectomax) is an antiparasitic agent. |
Kinase Assay | To determine which caspases are involved in apoptosis induced by taxol, caspase-3 inhibitor (DEVD-CHO), caspase-6 inhibitor (Z-VEID-FMK), caspase-8 inhibitor (Z-IETD-FMK or IETD-CHO), caspase-9 inhibitors (Z-LEHD-FMK or LEHD-CHO), and caspase-10 inhibitor (Z-AEVD-FMK) are used. These caspase inhibitors are dissolved in dimethyl sulfoxide (Me2SO); the final concentration of Me2SO is 0.1%. Cells (5×105) are preincubated in the presence or absence of 100 μM?each of these inhibitors for 3 h at 37°C then treated with or without 0.1, 0.5, and 1 μM?Paclitaxel for 48 h and processed for annexin V binding assay. |
Alias | Dectomax, Cyclohexylavermectin B1 |
Molecular Weight | 899.11 |
Formula | C50H74O14 |
Cas No. | 117704-25-3 |
Smiles | [H][C@@]12OC\C3=C/C=C/[C@H](C)[C@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)\C(C)=C\C[C@]4([H])C[C@@]([H])(C[C@@]5(O[C@H](C6CCCCC6)[C@@H](C)C=C5)O4)OC(=O)[C@]([H])(C=C(C)[C@H]1O)[C@@]23O |
Relative Density. | 1 114 kg/m3. Temperature:20 °C. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 30 mg/mL (33.37 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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