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ELR510444 (LR510444) is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM; not a substrate for the P-glycoprotein drug transporter and retains activity in βIII-tubulin-overexpressing cell lines.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | 32 € | In Stock | |
10 mg | 38 € | In Stock | |
25 mg | 69 € | In Stock | |
50 mg | 116 € | In Stock | |
100 mg | 188 € | In Stock | |
200 mg | 282 € | In Stock | |
1 mL x 10 mM (in DMSO) | 39 € | In Stock |
Description | ELR510444 (LR510444) is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM; not a substrate for the P-glycoprotein drug transporter and retains activity in βIII-tubulin-overexpressing cell lines. |
Alias | LR-510444, LR510444, LR 510444 |
Molecular Weight | 368.47 |
Formula | C19H16N2O2S2 |
Cas No. | 1233948-35-0 |
Smiles | Cc1ccc(cc1)S(=O)(=O)Nc1cc(ccc1C)-c1ccc(s1)C#N |
Relative Density. | 1.37 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (135.7 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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