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Fluocinonide

🥰Excellent
Catalog No. T6502Cas No. 356-12-7
Alias Topsyn, Metosyn, Lidex

Fluocinonide (Topsyn) (Vanos) is an effective glucocorticoid steroid, utilized in the treatment as the skin disorders anti-inflammatory agent.

Fluocinonide

Fluocinonide

🥰Excellent
Purity: 100%
Catalog No. T6502Alias Topsyn, Metosyn, LidexCas No. 356-12-7
Fluocinonide (Topsyn) (Vanos) is an effective glucocorticoid steroid, utilized in the treatment as the skin disorders anti-inflammatory agent.
Pack SizePriceAvailabilityQuantity
25 mg$33In Stock
50 mg$46In Stock
100 mg$66In Stock
200 mg$109In Stock
500 mg$219In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
Fluocinonide (Topsyn) (Vanos) is an effective glucocorticoid steroid, utilized in the treatment as the skin disorders anti-inflammatory agent.
In vitro
Fluocinonide can effectively induce and maintain pituitary-adrenal cortex suppression in dogs.
In vivo
Fluocinonide cream demonstrates lower efficacy for atrophic changes in the skin.
AliasTopsyn, Metosyn, Lidex
Chemical Properties
Molecular Weight494.52
FormulaC26H32F2O7
Cas No.356-12-7
Smiles[H][C@@]12C[C@@]3([H])[C@]4([H])C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]1(OC(C)(C)O2)C(=O)COC(C)=O
Relative Density.1.34g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 92 mg/mL (186 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0222 mL10.1108 mL20.2216 mL101.1081 mL
5 mM0.4044 mL2.0222 mL4.0443 mL20.2216 mL
10 mM0.2022 mL1.0111 mL2.0222 mL10.1108 mL
20 mM0.1011 mL0.5055 mL1.0111 mL5.0554 mL
50 mM0.0404 mL0.2022 mL0.4044 mL2.0222 mL
100 mM0.0202 mL0.1011 mL0.2022 mL1.0111 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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