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HBX 41108 (HBX-41108) is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBX 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $47 | In Stock | |
2 mg | $68 | In Stock | |
5 mg | $113 | In Stock | |
10 mg | $189 | In Stock | |
25 mg | $447 | In Stock | |
50 mg | $659 | In Stock | |
100 mg | $939 | In Stock |
Description | HBX 41108 (HBX-41108) is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBX 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM. |
Targets&IC50 | p53:0.8μM, USP7:424nM |
Alias | HBX-41108 |
Molecular Weight | 266.64 |
Formula | C13H3ClN4O |
Cas No. | 924296-39-9 |
Smiles | Clc1ccc-2c(c1)C(=O)c1nc(C#N)c(nc-21)C#N |
Relative Density. | 1.66 g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 60 mg/mL (225.02 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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