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IMB-301

🥰Excellent
Catalog No. T9212Cas No. 64009-84-3

IMB-301 is a small molecular inhibitor via virtual screening according to the hA3G model.

IMB-301

IMB-301

🥰Excellent
Purity: 99.72%
Catalog No. T9212Cas No. 64009-84-3
IMB-301 is a small molecular inhibitor via virtual screening according to the hA3G model.
Pack SizePriceAvailabilityQuantity
1 mg$41In Stock
5 mg$98In Stock
10 mg$158In Stock
25 mg$273In Stock
50 mg$389In Stock
100 mg$557In Stock
200 mg$758In Stock
1 mL x 10 mM (in DMSO)$107In Stock
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Purity:99.72%
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Product Introduction

Bioactivity
Description
IMB-301 is a small molecular inhibitor via virtual screening according to the hA3G model.
In vitro
IMB-301 binds to hA3G that interrupts the hA3G-Vif interaction and inhibits Vif-mediated degradation of hA3G.
Chemical Properties
Molecular Weight379.26
FormulaC19H17Cl2FN2O
Cas No.64009-84-3
SmilesFc1ccc(OCCC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1
Relative Density.1.27 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 90 mg/mL (237.3 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6367 mL13.1836 mL26.3671 mL131.8357 mL
5 mM0.5273 mL2.6367 mL5.2734 mL26.3671 mL
10 mM0.2637 mL1.3184 mL2.6367 mL13.1836 mL
20 mM0.1318 mL0.6592 mL1.3184 mL6.5918 mL
50 mM0.0527 mL0.2637 mL0.5273 mL2.6367 mL
100 mM0.0264 mL0.1318 mL0.2637 mL1.3184 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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