Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

IMR-1

🥰Excellent
Catalog No. T6861Cas No. 310456-65-6

IMR-1, a novel class of Notch inhibitors, targets transcriptional activation with an IC50 of 6 μMol/L.

IMR-1

IMR-1

🥰Excellent
Purity: 98.38%
Catalog No. T6861Cas No. 310456-65-6
IMR-1, a novel class of Notch inhibitors, targets transcriptional activation with an IC50 of 6 μMol/L.
Pack SizePriceAvailabilityQuantity
5 mg28 €In Stock
10 mg45 €In Stock
25 mg97 €In Stock
50 mg177 €In Stock
100 mg292 €In Stock
200 mg422 €In Stock
1 mL x 10 mM (in DMSO)50 €In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "IMR-1"

Select Batch
Purity:98.38%
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
IMR-1, a novel class of Notch inhibitors, targets transcriptional activation with an IC50 of 6 μMol/L.
Targets&IC50
Notch:6 μMol/L
Cell Research
ChIP assay on the HES1 promoter using the indicated antibodies following treatment of OE33 and 786-0 cells with DAPT (15 μM), IMR-1 (25 μM), or vehicle (DMSO) using GAPDH as loading control. (Only for Reference)
Chemical Properties
Molecular Weight353.41
FormulaC15H15NO5S2
Cas No.310456-65-6
SmilesCCOC(=O)COc1ccc(\C=C2\SC(=S)NC2=O)cc1OC
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 60 mg/mL (169.77 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8296 mL14.1479 mL28.2957 mL141.4787 mL
5 mM0.5659 mL2.8296 mL5.6591 mL28.2957 mL
10 mM0.2830 mL1.4148 mL2.8296 mL14.1479 mL
20 mM0.1415 mL0.7074 mL1.4148 mL7.0739 mL
50 mM0.0566 mL0.2830 mL0.5659 mL2.8296 mL
100 mM0.0283 mL0.1415 mL0.2830 mL1.4148 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy IMR-1 | purchase IMR-1 | IMR-1 cost | order IMR-1 | IMR-1 chemical structure | IMR-1 formula | IMR-1 molecular weight