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ISX-9
Catalog No. T2003Cas No. 832115-62-5
Alias Isoxazole 9 (ISX-9), Isoxazole 9
ISX-9 (Isoxazole 9) is essential for activating neuron-specific genes and serves as a neurogenesis inducer.
ISX-9
Catalog No. T2003Alias Isoxazole 9 (ISX-9), Isoxazole 9Cas No. 832115-62-5
ISX-9 (Isoxazole 9) is essential for activating neuron-specific genes and serves as a neurogenesis inducer.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $41 | In Stock | |
| 5 mg | $66 | In Stock | |
| 10 mg | $98 | In Stock | |
| 25 mg | $157 | In Stock | |
| 50 mg | $222 | In Stock | |
| 100 mg | $397 | In Stock | |
| 500 mg | $936 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $72 | In Stock |
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Purity:99.47%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | ISX-9 (Isoxazole 9) is essential for activating neuron-specific genes and serves as a neurogenesis inducer. |
| In vitro | In NSPCs, isoxazole 9 increases cell number, and promotes cell differentiation. In OPCs, isoxazole 9 induces cell damage. In outgrowth EPCs, isoxazole 9 decreases tube formation without effect on early EPCs. [1] |
| In vivo | In mice, isoxazole 9 (20 mg/kg, i.p.) crosses the BBB and increases proliferation of neuroblasts and neurogenesis via Mef2-specific mechanisms in the hippocampal SGZ. Isoxazole 9 (20 mg/kg, i.p.) also increases differentiation and dendritic complexity of immature neurons and improves memory. In MWM, isoxazole 9 improves spatial memory. [2] |
| Cell Research | Cells are treated with different concentrations of Isx-9 (0, 6.25, 12.5, 25, or 50 μM), and 2 days later, cell numbers are counted in a blinded manner to evaluate the effects of Isx-9 on the proliferation/survival of four types of progenitor/precursor cells.(Only for Reference) |
| Alias | Isoxazole 9 (ISX-9), Isoxazole 9 |
| Molecular Weight | 234.27 |
| Formula | C11H10N2O2S |
| Cas No. | 832115-62-5 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | Ethanol: 11 mg/mL (47 mM) DMSO: 40 mg/mL (170.74 mM)  | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
Ethanol/DMSO
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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