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Monastrol

🥰Excellent
Catalog No. T4048Cas No. 329689-23-8
Alias (±)-Monastrol

Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.

Monastrol

Monastrol

🥰Excellent
Purity: 99.19%
Catalog No. T4048Alias (±)-MonastrolCas No. 329689-23-8
Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.
Pack SizePriceAvailabilityQuantity
1 mg$40In Stock
5 mg$71In Stock
10 mg$98In Stock
25 mg$198In Stock
50 mg$328In Stock
100 mg$529In Stock
500 mg$1,130In Stock
1 mL x 10 mM (in DMSO)$89In Stock
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Purity:99.19%
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Product Introduction

Bioactivity
Description
Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.
Targets&IC50
KIF11(Eg5):14 μM
Alias(±)-Monastrol
Chemical Properties
Molecular Weight292.35
FormulaC14H16N2O3S
Cas No.329689-23-8
SmilesCCOC(=O)C1=C(C)NC(=S)NC1c1cccc(O)c1
Relative Density.1.34 g/cm3 at 20℃
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (188.13 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.4206 mL17.1028 mL34.2056 mL171.0279 mL
5 mM0.6841 mL3.4206 mL6.8411 mL34.2056 mL
10 mM0.3421 mL1.7103 mL3.4206 mL17.1028 mL
20 mM0.1710 mL0.8551 mL1.7103 mL8.5514 mL
50 mM0.0684 mL0.3421 mL0.6841 mL3.4206 mL
100 mM0.0342 mL0.1710 mL0.3421 mL1.7103 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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