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N-Desmethyl Pimavanserin
🥰Excellent
Catalog No. T37979Cas No. 639863-77-7
Alias AC-279
N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin, a 5-HT2A receptor inverse agonist, which is used in the treatment of sleep disorders such as insomnia.
N-Desmethyl Pimavanserin
🥰Excellent
Purity: 98.02%
Catalog No. T37979Alias AC-279Cas No. 639863-77-7
N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin, a 5-HT2A receptor inverse agonist, which is used in the treatment of sleep disorders such as insomnia.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $64 | In Stock | |
| 2 mg | $119 | In Stock | |
| 5 mg | $278 | In Stock | |
| 10 mg | $397 | In Stock | |
| 25 mg | $669 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $253 | In Stock |
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Purity:98.02%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin, a 5-HT2A receptor inverse agonist, which is used in the treatment of sleep disorders such as insomnia. |
| In vitro | For Pimavanserin and its metabolite N-Desmethyl Pimavanserin (AC-279), the mean plasma half-lives are 57 hours and 200 hours, respectively. |
| Alias | AC-279 |
| Molecular Weight | 413.53 |
| Formula | C24H32FN3O2 |
| Cas No. | 639863-77-7 |
| Smiles | CC(C)COc1ccc(CNC(=O)N(Cc2ccc(F)cc2)C2CCNCC2)cc1 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (120.91 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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