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Nexopamil
🥰Excellent
Catalog No. T28164Cas No. 136033-49-3
Alias LU-49938, LU49938, LU 49938
Nexopamil (LU-49938) is a calcium channel antagonist and a 5-hydroxytryptamine 2A receptor antagonist. Nexopamil inhibits 5-HT-induced contraction and proliferation of mesenchymal cells.
Nexopamil
🥰Excellent
Purity: 100%
Catalog No. T28164Alias LU-49938, LU49938, LU 49938Cas No. 136033-49-3
Nexopamil (LU-49938) is a calcium channel antagonist and a 5-hydroxytryptamine 2A receptor antagonist. Nexopamil inhibits 5-HT-induced contraction and proliferation of mesenchymal cells.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $120 | In Stock | |
| 5 mg | $290 | In Stock | |
| 10 mg | $440 | In Stock | |
| 25 mg | $728 | In Stock | |
| 50 mg | $987 | In Stock | |
| 100 mg | $1,390 | In Stock | |
| 500 mg | $2,770 | In Stock |
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Purity:100%
ee:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Nexopamil (LU-49938) is a calcium channel antagonist and a 5-hydroxytryptamine 2A receptor antagonist. Nexopamil inhibits 5-HT-induced contraction and proliferation of mesenchymal cells. |
| In vitro | Nexopamil abolished in a concentration-dependent way the serotonin-induced [3H]thymidine incorporation into DNA, and the serotonin-induced increase in a number of cells. Nexopamil partially blocked the serotonin-induced mesangial cell contraction, in a dose-dependent manner blocking 5-HT2 receptors and the voltage-operated Ca2+ channels.[3] |
| Alias | LU-49938, LU49938, LU 49938 |
| Molecular Weight | 404.59 |
| Formula | C24H40N2O3 |
| Cas No. | 136033-49-3 |
| Smiles | [C@@](CCCN(CCCCCC)C)(C(C)C)(C#N)C1=CC(OC)=C(OC)C(OC)=C1 |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (135.94 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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