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Nexopamil
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Nexopamil
Catalog No. T28164Cas No. 136033-49-3
Nexopamil (LU-49938) is a calcium channel antagonist and a 5-hydroxytryptamine 2A receptor antagonist. Nexopamil inhibits 5-HT-induced contraction and proliferation of mesenchymal cells.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $120 | In Stock | |
| 5 mg | $290 | In Stock | |
| 10 mg | $440 | In Stock | |
| 25 mg | $728 | In Stock | |
| 50 mg | $987 | In Stock | |
| 100 mg | $1,390 | In Stock | |
| 500 mg | $2,770 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Nexopamil (LU-49938) is a calcium channel antagonist and a 5-hydroxytryptamine 2A receptor antagonist. Nexopamil inhibits 5-HT-induced contraction and proliferation of mesenchymal cells. |
| In vitro | Nexopamil abolished in a concentration-dependent way the serotonin-induced [3H]thymidine incorporation into DNA, and the serotonin-induced increase in a number of cells. Nexopamil partially blocked the serotonin-induced mesangial cell contraction, in a dose-dependent manner blocking 5-HT2 receptors and the voltage-operated Ca2+ channels.[3] |
| Alias | LU49938, LU 49938, LU-49938 |
| Molecular Weight | 404.59 |
| Formula | C24H40N2O3 |
| Cas No. | 136033-49-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (135.94 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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