Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Oleandrin

🥰Excellent
Catalog No. T5S0890Cas No. 465-16-7
Alias Neriostene, Folinerin, Foliandrin

1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, K-ATPase pump, resulting in a consequent increase in calcium influx in heart muscle. 3. Oleandrin has stronger anti-proliferative activity in undifferentiated CaCO-2 cells (IC50, 8.25 nM) , causes an autophagic cell death and altered ERK phosphorylation in undifferentiated.

Oleandrin

Oleandrin

🥰Excellent
Purity: 99.94%
Catalog No. T5S0890Alias Neriostene, Folinerin, FoliandrinCas No. 465-16-7
1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, K-ATPase pump, resulting in a consequent increase in calcium influx in heart muscle. 3. Oleandrin has stronger anti-proliferative activity in undifferentiated CaCO-2 cells (IC50, 8.25 nM) , causes an autophagic cell death and altered ERK phosphorylation in undifferentiated.
Pack SizePriceAvailabilityQuantity
1 mg$98In Stock
2 mg$147In Stock
5 mg$289In Stock
10 mg$463In Stock
25 mg$763In Stock
50 mg$1,070In Stock
100 mg$1,430In Stock
500 mg$2,890In Stock
1 mL x 10 mM (in DMSO)$367In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "Oleandrin"

Select Batch
Purity:99.94%
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, K-ATPase pump, resulting in a consequent increase in calcium influx in heart muscle. 3. Oleandrin has stronger anti-proliferative activity in undifferentiated CaCO-2 cells (IC50, 8.25 nM) , causes an autophagic cell death and altered ERK phosphorylation in undifferentiated.
Targets&IC50
Na+, K+-ATPase:620 nM (IC50)
AliasNeriostene, Folinerin, Foliandrin
Chemical Properties
Molecular Weight576.72
FormulaC32H48O9
Cas No.465-16-7
Smiles[H][C@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)[C@H]([C@H](C[C@]34O)OC(C)=O)C3=CC(=O)OC3)[C@@]1(C)CC[C@@H](C2)O[C@H]1C[C@H](OC)[C@@H](O)[C@H](C)O1
Relative Density.1.26 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: Soluble
Pyridine, Methanol, etc.: Soluble
DMSO: 60 mg/ml (104.04 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7339 mL8.6697 mL17.3394 mL86.6972 mL
5 mM0.3468 mL1.7339 mL3.4679 mL17.3394 mL
10 mM0.1734 mL0.8670 mL1.7339 mL8.6697 mL
20 mM0.0867 mL0.4335 mL0.8670 mL4.3349 mL
50 mM0.0347 mL0.1734 mL0.3468 mL1.7339 mL
100 mM0.0173 mL0.0867 mL0.1734 mL0.8670 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Oleandrin | purchase Oleandrin | Oleandrin cost | order Oleandrin | Oleandrin chemical structure | Oleandrin formula | Oleandrin molecular weight