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By Target- ATPase
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Results for "
pbi 05204
" in TargetMol Product Catalog- Inhibitors & Agonists1
- Natural Products1
Oleandrin
Cited
Neriostene,Folinerin,Foliandrin
T5S0890465-16-7
1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, K-ATPase pump, resulting in a consequent increase in calcium influx in heart muscle. 3. Oleandrin has stronger anti-proliferative activity in undifferentiated CaCO-2 cells (IC50, 8.25 nM) , causes an autophagic cell death and altered ERK phosphorylation in undifferentiated.
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