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Oxantel Pamoate (Oxantel embonate) is used as an Antinematodal agent.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
200 mg | $31 | In Stock | |
500 mg | $48 | In Stock | |
1 g | $70 | In Stock | |
5 g | $168 | In Stock | |
1 mL x 10 mM (in DMSO) | $29 | In Stock |
Description | Oxantel Pamoate (Oxantel embonate) is used as an Antinematodal agent. |
In vivo | The efficacy of the veterinary drug Oxantel pamoate against Trichuris muris, Ancylostoma ceylanicum, and Necator americanus was evaluated, revealing an ED50s of 4.7 mg/kg for T. muris in mice. When combined with pyrantel pamoate, Oxantel pamoate showed an antagonistic interaction (CI=2.53). Similarly, combinations with Levamisole, Albendazole, or Ivermectin, based on their ED50s, also demonstrated antagonistic effects (CIs of 1.27, 1.90, and 1.27, respectively). Conversely, a combination with mebendazole exhibited a highly synergistic effect (CI=0.15) against T. muris infection. At a dosage of 10 mg/kg, Oxantel pamoate was ineffective against A. ceylanicum and N. americanus[1]. |
Alias | Oxantel embonate |
Molecular Weight | 604.65 |
Formula | C36H32N2O7 |
Cas No. | 68813-55-8 |
Smiles | CN1CCCN=C1\C=C\c1cccc(O)c1.OC(=O)c1cc2ccccc2c(Cc2c(O)c(cc3ccccc23)C(O)=O)c1O |
Relative Density. | 1.09 g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 60 mg/mL (99.23 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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