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P-Hydroxyphenethyl trans-ferulate

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Catalog No. TN2030Cas No. 84873-15-4

P-Hydroxyphenethyl trans-ferulate exhibits affinity toward 5-HT(7) receptors in a competitive binding assay. P-Hydroxyphenethyl trans-ferulate can double quinone reductase specific activity in Hepa 1c1c7 cells at a level of 2.1 microg/mL (6.6 microM).

P-Hydroxyphenethyl trans-ferulate

P-Hydroxyphenethyl trans-ferulate

🥰Excellent
Purity: 99.3%
Catalog No. TN2030Cas No. 84873-15-4
P-Hydroxyphenethyl trans-ferulate exhibits affinity toward 5-HT(7) receptors in a competitive binding assay. P-Hydroxyphenethyl trans-ferulate can double quinone reductase specific activity in Hepa 1c1c7 cells at a level of 2.1 microg/mL (6.6 microM).
Pack SizePriceAvailabilityQuantity
1 mg$89In Stock
5 mg$226In Stock
10 mg$337In Stock
25 mg$569In Stock
50 mgInquiryIn Stock
1 mL x 10 mM (in DMSO)$239In Stock
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Purity:99.3%
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Product Introduction

Bioactivity
Description
P-Hydroxyphenethyl trans-ferulate exhibits affinity toward 5-HT(7) receptors in a competitive binding assay. P-Hydroxyphenethyl trans-ferulate can double quinone reductase specific activity in Hepa 1c1c7 cells at a level of 2.1 microg/mL (6.6 microM).
In vitro
Crude nonpolar solvent extracts were prepared from freeze-dried green onion by sequential refluxing with hexane and then ethyl acetate, followed by liquid-liquid extraction. Active fractions were subjected to the Hepa 1c1c7 bioassay-guided steps of flash chromatography, thin layer chromatography (TLC), and high-pressure preparative liquid chromatography (HPLC) to afford pure isolates capable of inducing QR. Multiple fractions were active in inducing QR. Five pure compounds were isolated from active fractions and identified using spectroscopic methods; these were p-Hydroxyphenethyl trans-ferulate (1), 5,6-dimethyl-2-pyridinecarboxylic acid (2), ferulic acid (3), 1-(6-hydroxy-[3]pyridyl)-propan-1-one (4), and N-trans-feruloyl 3-O-methyldopamine (5).
Chemical Properties
Molecular Weight314.33
FormulaC18H18O5
Cas No.84873-15-4
SmilesCOc1cc(\C=C\C(=O)OCCc2ccc(O)cc2)ccc1O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/ml (174.98 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.1814 mL15.9068 mL31.8137 mL159.0685 mL
5 mM0.6363 mL3.1814 mL6.3627 mL31.8137 mL
10 mM0.3181 mL1.5907 mL3.1814 mL15.9068 mL
20 mM0.1591 mL0.7953 mL1.5907 mL7.9534 mL
50 mM0.0636 mL0.3181 mL0.6363 mL3.1814 mL
100 mM0.0318 mL0.1591 mL0.3181 mL1.5907 mL

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