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Parbendazole
🥰Excellent
Catalog No. T6071Cas No. 14255-87-9
Alias SKF 29044
Parbendazole (SKF 29044) is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine. It finds applications in control or treatment of nematode infestations.
Parbendazole
🥰Excellent
Catalog No. T6071Alias SKF 29044Cas No. 14255-87-9
Parbendazole (SKF 29044) is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine. It finds applications in control or treatment of nematode infestations.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | 43 € | In Stock | |
| 25 mg | 67 € | In Stock | |
| 50 mg | 93 € | In Stock | |
| 100 mg | 163 € | In Stock | |
| 200 mg | 244 € | In Stock | |
| 1 mL x 10 mM (in DMSO) | 47 € | In Stock |
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Parbendazole (SKF 29044) is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine. It finds applications in control or treatment of nematode infestations. |
| Targets&IC50 | Microtubule:8.79 nM(EC50) |
| In vitro | Parbendazole is a tubulin destabilizer with an EC50 of 8.79 nM that can induce DNA damage[1]. It inhibits microtubule assembly dose-dependently, with an IC50 of 3 μM, and treatment with 2-20 μM results in the complete absence of microtubules in Vero cells[2]. |
| Alias | SKF 29044 |
| Molecular Weight | 247.29 |
| Formula | C13H17N3O2 |
| Cas No. | 14255-87-9 |
| Smiles | CCCCc1ccc2[nH]c(NC(=O)OC)nc2c1 |
| Relative Density. | 1.1214 g/cm3 (Estimated) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 4 mg/mL (16.18 mM) | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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