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PfDHODH-IN-2

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Catalog No. T8767Cas No. 425629-94-3

PfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 μM) inhibitor . It is used an antimalarial agent and can be used for the research of malaria

PfDHODH-IN-2

PfDHODH-IN-2

🥰Excellent
Purity: 98.90%
Catalog No. T8767Cas No. 425629-94-3
PfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 μM) inhibitor . It is used an antimalarial agent and can be used for the research of malaria
Pack SizePriceAvailabilityQuantity
1 mg38 €In Stock
5 mg93 €In Stock
10 mg140 €In Stock
25 mg259 €In Stock
50 mg382 €In Stock
100 mg544 €In Stock
200 mg740 €In Stock
1 mL x 10 mM (in DMSO)101 €In Stock
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Purity:98.90%
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Product Introduction

Bioactivity
Description
PfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 μM) inhibitor . It is used an antimalarial agent and can be used for the research of malaria
Targets&IC50
DHODH (human):>50 µM (IC50), PfDHODH:1.113 µM (IC50)
Chemical Properties
Molecular Weight297.76
FormulaC13H12ClNO3S
Cas No.425629-94-3
SmilesCCOC(=O)C1=C(Nc2ccc(Cl)cc2)SCC1=O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 12 mg/mL (40.3 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3584 mL16.7920 mL33.5841 mL167.9205 mL
5 mM0.6717 mL3.3584 mL6.7168 mL33.5841 mL
10 mM0.3358 mL1.6792 mL3.3584 mL16.7920 mL
20 mM0.1679 mL0.8396 mL1.6792 mL8.3960 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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